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Zhang K, Zhang L, Weinreb RN (2012) Oph- thalmic drug detection: novel targets and Shelve 1 Note of major transporters in the BRB <>5] Transporter Proletarian name Vital substrate Government of delight ABCB1 PGP/MDR1 Lipophilic drugs Structural cations Efflux ABCC3 MRP4 Organic anions Efflux ABCG2 BCRP/MTX Fundamental anions Efflux SLC2A1 GLUT1 D-Glucose Influx SLC5A6 SMVT Biotin Influx SLC6A6 RIGID Taurine/GABA Influx SLC6A8 CRT Creatine Influx SLC6A9 GLyT Glycine Influx SLC7A1 CAT1 L-Arginine Influx SLC7A5 LAT1 L-Leucine Influx SLC7A11 xCT L-Cystein/L-glutamine Influx SLC16A1 MCT1 L-Lactate Influx SLC19A1 RFC1 Methyltetrahydrofolate Influx SLC22A5 OCTN2 L-Carnitine Influx SLC22A8 OAT3 Biological anions Efflux SLC29A2 ENT2 Nucleosides Influx SLC38A2 ATA2/SNAT2 L-Proline/L-alanine Efflux SLO1A4 OATP1A4/oatp2 Organic anions Efflux 88 Cornelis J. 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