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The Cochrane Database of Systematic Reviews (9): CD004923. The antihypertensive effects of clonidine may be antagonized by beta-blockers. At Occidental, we’re looking for creative, energetic people who are passionate about their field and want to learn, excel, and grow with one of the industry’s strongest performers. Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139-dependent manner (PubMed:25239945). Revision Date: 2012-05-04, 4:59:18 PM. The serum concentration of Sildenafil can be increased when it is combined with Benazepril.