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If you have trouble swallowing an extended-release capsule whole, ask your doctor or pharmacist if it is safe for you to open the capsule and sprinkle the medicine into a spoonful of applesauce to make swallowing easier. These factors may worsen symptoms of morphine toxicity. Citalopram is frequently used off-label to treat anxiety, panic disorder, dysthymia, <>2] premenstrual dysphoric disorder, body dysmorphic disorder, and obsessive–compulsive disorder. Patients Receiving Sulfonylureas or Insulin: Sulfonylurea agents or insulin may cause hypoglycemia. In vitro drug metabolism studies reveal that trazodone is a substrate of the cytochrome P450 3A4 (CYP3A4) enzyme and trazodone metabolism can be inhibited by the CYP3A4 inhibitors ketoconazole, ritonavir, and indinavir. After about a year and a half, it would be possible for lithium carbonate to be chemically separated from the remaining elements.
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